منابع مشابه
Piroxicam-β-Cyclodextrin: A GI Safer Piroxicam
Although NSAIDs are very effective drugs, their use is associated with a broad spectrum of adverse reactions in the liver, kidney, cardiovascular (CV) system, skin and gut. Gastrointestinal (GI) side effects are the most common and constitute a wide clinical spectrum ranging from dyspepsia, heartburn and abdominal discomfort to more serious events such as peptic ulcer with life-threatening comp...
متن کاملNew Crystalline Forms of Piroxicam
Four new crystalline forms of piroxicam have been obtained and studied by single-crystal X-ray structure analysis. These comprise an addition salt with hydrochloric acid, acetic and isobutyric acids solvates, as well as piroxicam and furosemide cocrystal acetone solvate. All these new structures contribute to the variety of already known piroxicam crystalline forms. The analysis of conformation...
متن کامل[Fixed drug eruption due to piroxicam].
Piroxicam is a nonsteroidal antiinflammatory drug (NSAID) of the oxicam group and has anti-inflammatory, analgesic, antipyretic, and antiplatelet properties. It is a potent prostaglandin inhibitor with a long half-life in plasma (36-58 hours), meaning that it can be administered in a single daily dose. Multiple adverse systemic effects have been reported for piroxicam, of which the most common ...
متن کاملStimulation of apoptosis by sulindac and piroxicam.
1.Sulindac, cis-5-fluoro-2-methyl-1-(p-methylsulphinylbenzylidene)indene-3-ace tic acid, inhibits growth of colon polyps and cancers. This effect has been attributed to inhibition of prostaglandin synthesis but more recent observations indicate that, in vitro, cells that do not have cyclo-oxygenase nor RNA for synthesis of such enzymes are affected by sulindac. Therefore the presumptive effect ...
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ژورنال
عنوان ژورنال: BMJ
سال: 1983
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.287.6395.798